The APIs themselves are online and appear to be in good health. Have you started doing anything differently with WAX in the past 48 hours?
We do have rate limits on our APIs, meaning you can only make so many requests per second to the servers before they start blocking you. I know there are some users who have used various game mining tools developed by the community, which spam transactions pretty fast, and then up getting the user blocked for periods of time.
This block is by IP address - so it’d also prevent Anchor from connecting.